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While the sequence forms the proper “landing surface” of telomeric DNA, its length is similarly important. The telomere sequence is important as a “landing area” for specific telomere-binding proteins, which function as signals and moderate the interactions required for correct telomere function. There are two basic characteristics of telomeric DNA, its sequence and its length. They shelter the terminal genome territories against degradation and prevent the natural chromosome ends from being recognized by repair mechanisms as double-strand DNA breaks. Telomeres are essential nucleoprotein structures at the very ends of linear eukaryote chromosomes.
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